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韓國(guó)LCI產(chǎn)制滿足各種應(yīng)用培養(yǎng)系統(tǒng)其他設(shè)備電生理/IVF
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LCI |
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韓國(guó)LCI |
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2025-02-24 |
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Multistep paradigm for leukocyte recruitment.
(
a) Model of a post-capillary venule illustrating the four steps of leukocyte recruitment. These are (1) initial attachment (2) low-velocity rolling (3) arrest and activation of leukocyte integrin
via locally expressed chemokines and (4) transmigration. (
b) Fluid shear stress. In small venules, flow has been calculated as laminar shear stress with a parabolic velocity profile (minimum velocity at the vessel wall, maximum at the center line of the vessel). Fluid shear stress also can act directly on endothelial cells and T cells. (EC, endothelial cell; BM, basement membrane.) (Reprinted with permission from Alper, J. Searching for medicine's sweet spot.
Science 291, 2338−2243 (2001).). Copyright American Association for the Advancement of Science. Original illustration by C. Cain, redrawn by B. Crimi.)